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5 BAR CIGARETTE PICU 1 DNA MUTATIONS

London, researchers found every 15 cigarettes consumed the DNA mutations occur in a smoker's body is. Imagine if that consumed more than that. This is obtained after mapping the genetic researcher from patients with lung cancer.

Researchers from England who did this study to identify the 23,000 mutation is responsible for any damage caused by the chemicals contained in cigarette smoke.

As we know all cancers are caused by errors in the genetic code (mutation in the DNA) which is usually triggered by the environment. Researchers hope this discovery can develop new treatments.

Genetic defect from one to hundreds of changes in the code, this change could be the deletion or rearrangement of these codes. No single mutation alone can cause a disease. Instead most cancers occur due to various combinations of what happened.

"This knowledge is expected to be influential in future treatments. Be able to identify genes with cancer, the development of future treatments could be a way to target specific genes to mutate," said study leader Dr Peter Campbell from the Wellcome Trust Sanger Institute in Cambridgeshire, as quoted from Dailymail, Friday (18/12/2009).

Cancer occurs when an uncontrolled behavior of cells that can not grow properly. Gene mutation triggers one of them caused by cigarette smoke is passed to every subsequent generation of cells such as children, causing permanent descent can be derived.

Every 15 cigarettes consumed could lead to a mutation of DNA in the body and these mutations can be accumulated. Researchers have found a risk of lung cancer risk can be reduced as a normal person after quitting smoking for 15 years.

The scientists suspect that the lung cells that contain these harmful mutations would be replaced by new cells that are free from defects. Researchers conducted 60 times DNA sequencing (determining the sequence of nucleotide bases in a DNA fragment) for lung cancer in order to give accurate results.

For the disease of lung cancer is caused mostly by exposure to cigarette smoke, so the disease is not only attacking smokers, but also people around who become passive smokers. With the discovery of the genome sequence, then the mold can be obtained from the mutated gene that can cause tumors or cancer.

If every 15 cigarettes consumed could cause a mutation of DNA in the body, then in the next few years this DNA mutations will accumulate in the body that can cause cancer. Because it does not hurt to start quit smoking from now.

sources detik, Vera Farah Bararah - detikHealth

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